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PABPN1 抗体 (AA 100-150)

This anti-PABPN1 antibody is a 兔 多克隆 antibody detecting PABPN1 in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7454923
发货至: 中国

Quick Overview for PABPN1 抗体 (AA 100-150) (ABIN7454923)

抗原

See all PABPN1 抗体
PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))

适用

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宿主

  • 30

克隆类型

  • 18
  • 12
多克隆

标记

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This PABPN1 antibody is un-conjugated

应用范围

  • 22
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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 100-150

    原理

    Rabbit anti-PABPN1 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 100 and 150

    亚型

    IgG
  • 应用备注

    IHC: 1:200 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))

    别名

    PABPN1

    背景

    Background: Polyadenylate binding protein, nuclear 1 (PABPN1) is involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product. PABPN1 stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and also controls the poly(A) tail length. PABPN1 increases the affinity of poly(A) polymerase for RNA and is also present at various stages of mRNA metabolism including nucleocytoplasmic trafficking and nonsense-mediated decay (NMD) of mRNA [taken from the Universal Protein Resource (UniProt) Q86U42].

    基因ID

    8106

    NCBI登录号

    NP_004634

    UniProt

    Q86U42
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