PABPN1 抗体 (AA 100-150)
Quick Overview for PABPN1 抗体 (AA 100-150) (ABIN7454923)
抗原
See all PABPN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-150
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原理
- Rabbit anti-PABPN1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 100 and 150
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亚型
- IgG
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应用备注
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IHC: 1:200 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))
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别名
- PABPN1
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背景
- Background: Polyadenylate binding protein, nuclear 1 (PABPN1) is involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product. PABPN1 stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and also controls the poly(A) tail length. PABPN1 increases the affinity of poly(A) polymerase for RNA and is also present at various stages of mRNA metabolism including nucleocytoplasmic trafficking and nonsense-mediated decay (NMD) of mRNA [taken from the Universal Protein Resource (UniProt) Q86U42].
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基因ID
- 8106
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NCBI登录号
- NP_004634
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UniProt
- Q86U42
抗原
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