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RAD23B 抗体 (AA 359-409)

This anti-RAD23B antibody is a 兔 多克隆 antibody detecting RAD23B in WB, IP 和 IHC (fp). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7454820
发货至: 中国

Quick Overview for RAD23B 抗体 (AA 359-409) (ABIN7454820)

抗原

See all RAD23B 抗体
RAD23B (RAD23 Homolog B (RAD23B))

适用

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人, 小鼠, 大鼠

宿主

  • 66
  • 20
  • 1

克隆类型

  • 67
  • 20
多克隆

标记

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This RAD23B antibody is un-conjugated

应用范围

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  • 1
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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 15
    • 8
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    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 359-409

    原理

    Rabbit anti-RAD23B Antibody, Affinity Purified

    预测反应

    Bovine

    纯化方法

    Affinity Purified

    免疫原

    between AA 359 and 409

    亚型

    IgG
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    RAD23B (RAD23 Homolog B (RAD23B))

    别名

    RAD23B

    背景

    Background: RAD23B is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. RAD23B was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

    基因ID

    5887

    NCBI登录号

    NP_002865

    UniProt

    P54727

    途径

    DNA Damage Repair
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