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DDB1 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects DDB1 in WB, IP 和 IHC (fp). It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN7454634
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for DDB1 抗体 (C-Term) (ABIN7454634)

抗原

See all DDB1 抗体
DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))

适用

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  • 1
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人, 小鼠

宿主

  • 47
  • 7
  • 1

克隆类型

  • 35
  • 20
多克隆

标记

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  • 2
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  • 1
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This DDB1 antibody is un-conjugated

应用范围

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  • 1
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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 8
    • 5
    • 2
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    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Rabbit anti-DDB1 Antibody, Affinity Purified

    预测反应

    Rat,X. laevis,Bovine,Orangutan

    纯化方法

    Affinity Purified

    免疫原

    between AA 1100 and C-term

    亚型

    IgG
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))

    别名

    DDB1

    背景

    Background: DDB1 (DNA Damage Binding Protein 1) is a subunit of the DNA damage-binding protein complex (DDB) involved in DNA repair. As part of a complex with Cul4-based ubiquitin ligase, Cul4-Ddb1 can directly modify chromatin through the ubiquitination of histones as well as ubiquitinate other chromatin bound factors. A deficiency in Cul4-Ddb1 ubiquitin ligase has been associated with xeroderma pigmentosum, a heritable disease characterized by defects in nucleotide excision repair and skin cancer development.

    基因ID

    1642

    UniProt

    Q16531, Q13289

    途径

    DNA Damage Repair
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