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CBP 抗体 (AA 2375-2425)

This anti-CBP antibody is a 兔 多克隆 antibody detecting CBP in WB, IP 和 IHC (fp). Suitable for 人.
产品编号 ABIN7454618
发货至: 中国

Quick Overview for CBP 抗体 (AA 2375-2425) (ABIN7454618)

抗原

See all CBP (CREBBP) 抗体
CBP (CREBBP) (CREB Binding Protein (CREBBP))

适用

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宿主

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克隆类型

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多克隆

标记

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This CBP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
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    AA 2375-2425

    原理

    Rabbit anti-CBP Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 2375 and 2425

    亚型

    IgG
  • 应用备注

    IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 1 - 4 μg/mg lysate

    WB: 1:1,000 - 1:25,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    CBP (CREBBP) (CREB Binding Protein (CREBBP))

    别名

    CBP

    背景

    Background: CBP [cAMP response element-binding protein (CREB)-binding protein] interacts with and is a transcriptional co-activator of a multitude of transcriptional regulators that includes CREB. CBP is structurally and functionally similar to p300 but is encoded by an independent gene. CBP coactivation may be achieved through the regulation of chromatin structure due to its ability to catalyze the acetylation of histones. CBP has potential tumor suppressor properties and is important to integrating cell-signaling cues for proliferation, differentiation and apoptosis.

    基因ID

    1387

    NCBI登录号

    NP_004371

    UniProt

    Q92793

    途径

    TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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