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CBP 抗体 (C-Term)

CREBBP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260516
发货至: 中国
  • 抗原 See all CBP (CREBBP) 抗体
    CBP (CREBBP) (CREB Binding Protein (CREBBP))
    抗原表位
    • 11
    • 8
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    • 5
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    • 2
    • 2
    • 1
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    C-Term
    适用
    • 79
    • 37
    • 31
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
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    人, 小鼠, 大鼠
    宿主
    • 77
    • 6
    克隆类型
    • 77
    • 6
    多克隆
    标记
    • 42
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    This CBP antibody is un-conjugated
    应用范围
    • 65
    • 44
    • 22
    • 19
    • 11
    • 11
    • 11
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    CREB-BP Antibody detects endogenous levels of total CREB-BP.
    预测反应
    Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human CREB-BP, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CREBBP Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    CBP (CREBBP) (CREB Binding Protein (CREBBP))
    别名
    CREBBP (CREBBP 产品)
    别名
    CBP antibody, KAT3A antibody, RSTS antibody, AW558298 antibody, CBP/p300 antibody, p300/CBP antibody, RTS antibody, cbp antibody, crebbp antibody, kat3a antibody, rsts antibody, hmm291030 antibody, Nejire antibody, CREB binding protein antibody, CREB binding protein L homeolog antibody, histone acetyltransferase p300 antibody, CREBBP antibody, Crebbp antibody, crebbp.L antibody, LOC100123220 antibody
    背景

    Description: Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Acetylates PCNA, acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER) (PubMed:24939902).

    Gene: CREBBP

    分子量
    265kDa
    基因ID
    1387
    UniProt
    Q92793
    途径
    TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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