CBP 抗体 (N-Term)
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北京 101111
Quick Overview for CBP 抗体 (N-Term) (ABIN2781491)
抗原
See all CBP (CREBBP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- CREBBP Antibody - N-terminal region
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序列
- TPAASQALNP QAQKQVGLAT SSPATSQTGP GICMNANFNQ THPGLLNSNS
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against CREBBP. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CREBBP
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43609-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CBP (CREBBP) (CREB Binding Protein (CREBBP))
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别名
- CREBBP
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背景
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Background Information: CREBBP is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. CREBBP has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain.
Gene Name: CREB binding protein
Alternative Symbols: CBP, RSTS, KAT3A, MKHK1, RSTS1
Protein Name: CREBBP variant protein EMBL BAE06125.1
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分子量
- 261kDa
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基因ID
- 1387
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NCBI登录号
- NP_001073315
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UniProt
- Q4LE28
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途径
- TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
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