p300 抗体 (AA 1000-1050)
Quick Overview for p300 抗体 (AA 1000-1050) (ABIN7454617)
抗原
See all p300 (EP300) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1000-1050
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原理
- Rabbit anti-p300 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 1000 and 1050
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亚型
- IgG
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:1,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- p300 (EP300) (E1A Binding Protein P300 (EP300))
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别名
- p300
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背景
- Background: By sequence similarity p300 is related to CBP (CREB-binding protein) and functions as a histone acetyltransferase that can regulate transcription by influencing chromatin organization. P300 has been demonstrated to bind to phosphorylated CREB to mediate cAMP-gene regulation. P300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha).
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基因ID
- 2033
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NCBI登录号
- NP_001420
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UniProt
- Q09472
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途径
- p53 Pathway, Notch Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size
抗原
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