FEN1 抗体 (AA 250-300)
Quick Overview for FEN1 抗体 (AA 250-300) (ABIN7454602)
抗原
See all FEN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 250-300
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原理
- Rabbit anti-Fen1 Antibody, Affinity Purified
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预测反应
- Sheep,Bovine
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纯化方法
- Affinity Purified
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免疫原
- between AA 250 and 300
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亚型
- IgG
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应用备注
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IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. 16-18 hour incubation is recommended.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))
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别名
- Fen1
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背景
- Background: Flap endonuclease 1 (Fen1) is a member of the XPG/RAD2 endonuclease family. Fen1 functions primarily as an endonuclease that removes 5'-overhangs during base-excision DNA repair and lagging strand DNA synthesis. For these processes Fen1 interacts with PCNA and the 9-1-1 DNA repair complex. Fen1 also possesses 5' to 3' exonuclease activity as well as RNase H activity.
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基因ID
- 2237
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NCBI登录号
- NP_004102
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UniProt
- P39748
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途径
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
抗原
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