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FEN1 抗体

FEN1 适用: 人, 小鼠 WB, ICC 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6241657
发货至: 中国
  • 抗原 See all FEN1 抗体
    FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))
    适用
    • 62
    • 42
    • 37
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 58
    • 8
    小鼠
    克隆类型
    • 56
    • 10
    单克隆
    标记
    • 42
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FEN1 antibody is un-conjugated
    应用范围
    • 54
    • 17
    • 16
    • 13
    • 13
    • 11
    • 9
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC)
    免疫原
    Recombinant Protein
    Top Product
    Discover our top product FEN1 Primary Antibody
  • 应用备注
    WB: 1:1000. ICC: 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    储存条件
    4 °C,-20 °C
  • 抗原
    FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))
    别名
    FEN-1 (FEN1 产品)
    别名
    FEN-1 antibody, FEN1 antibody, AW538437 antibody, MF1 antibody, RAD2 antibody, cb879 antibody, fen-1 antibody, fen1 antibody, mf1 antibody, rad2 antibody, xFEN1a antibody, flap structure-specific endonuclease 1 antibody, flap endonuclease 1-like antibody, Flap endonuclease-1 antibody, 5'-3' exonuclease family protein antibody, flap structure specific endonuclease 1 antibody, flap structure-specific endonuclease 1 L homeolog antibody, nuclease, Rad2 family antibody, FEN1 antibody, LOC100808044 antibody, Bm1_49605 antibody, AT5G26680 antibody, Fen1 antibody, fen1 antibody, fen1.L antibody
    背景
    Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double- stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
    UniProt
    P39748
    途径
    Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
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