Cullin 1 抗体 (AA 250-300)
Quick Overview for Cullin 1 抗体 (AA 250-300) (ABIN7454487)
抗原
See all Cullin 1 (CUL1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 250-300
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原理
- Rabbit anti-Cul1 Antibody, Affinity Purified
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预测反应
- Mouse,Orangutan
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纯化方法
- Affinity Purified
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免疫原
- between AA 250 and 300
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亚型
- IgG
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: Not recommended
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Cullin 1 (CUL1)
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别名
- Cul1
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背景
- Background: Cullin 1 (Cul1) is the core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, Cul1 serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. Cul1 may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme [taken from the Universal Protein Resource (UniProt) Q13616].
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基因ID
- 8454
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NCBI登录号
- NP_003583
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UniProt
- Q13616
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途径
- Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases, Regulation of Cell Size
抗原
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