TFAM 抗体 (AA 146-196)
Quick Overview for TFAM 抗体 (AA 146-196) (ABIN7454483)
抗原
See all TFAM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 146-196
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原理
- Rabbit anti-TFAM Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 146 and 196
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亚型
- IgG
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: Not recommended
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- TFAM (Transcription Factor A, Mitochondrial (TFAM))
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别名
- TFAM
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背景
- Background: Transcription factor A, mitochondrial (TFAM) binds to the mitochondrial light strand promoter and functions in mitochondrial transcriptional regulation. TFAM is required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase and promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. TFMA is required for maintenance of normal levels of mitochondrial DNA and may play a role in organizing and compacting mitochondrial DNA [taken from the Universal Protein Resource (UniProt) Q00059].
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基因ID
- 7019
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NCBI登录号
- NP_003192
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UniProt
- Q00059
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途径
- Chromatin Binding
抗原
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