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HEXIM1 抗体 (AA 1-50)

This 兔 多克隆 antibody specifically detects HEXIM1 in IP 和 IHC (fp). It exhibits reactivity toward 人.
产品编号 ABIN7454478
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for HEXIM1 抗体 (AA 1-50) (ABIN7454478)

抗原

See all HEXIM1 抗体
HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))

适用

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宿主

  • 65
  • 9
  • 1
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克隆类型

  • 69
  • 7
多克隆

标记

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This HEXIM1 antibody is un-conjugated

应用范围

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Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 10
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    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
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    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-50

    原理

    Rabbit anti-HEXIM1 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 1 and 50

    亚型

    IgG
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: Not recommended

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))

    别名

    HEXIM1

    背景

    Background: Hexamethylene bis-acetamide-inducible protein 1 (HEXIM1) is a transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA, HEXIM1sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. HEXIM1 may also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity [taken from the Universal Protein Resource (UniProt) O94992].

    基因ID

    10614

    NCBI登录号

    NP_006451

    UniProt

    O94992
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