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HEXIM1 抗体

HEXIM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262224
发货至: 中国
  • 抗原 See all HEXIM1 抗体
    HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))
    适用
    • 67
    • 54
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    人, 小鼠, 大鼠
    宿主
    • 64
    • 7
    • 1
    • 1
    克隆类型
    • 68
    • 5
    多克隆
    标记
    • 41
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    • 3
    • 1
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    This HEXIM1 antibody is un-conjugated
    应用范围
    • 69
    • 34
    • 33
    • 13
    • 12
    • 11
    • 6
    • 3
    • 2
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    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    HEXIM1 Antibody detects endogenous levels of HEXIM1
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human HEXIM1
    亚型
    IgG
    Top Product
    Discover our top product HEXIM1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IF/ICC 1:100-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))
    别名
    HEXIM1 (HEXIM1 产品)
    别名
    HEXIM1 antibody, fd44h02 antibody, hexim antibody, wu:fd44h02 antibody, zgc:162976 antibody, CLP1 antibody, EDG1 antibody, HIS1 antibody, MAQ1 antibody, 7330426E13Rik antibody, CLP-1 antibody, Clp1 antibody, Clp-1 antibody, hexamethylene bisacetamide inducible 1 antibody, hexamethylene bis-acetamide inducible 1 antibody, hexamethylene bis-acetamide inducible 1 L homeolog antibody, HEXIM1 antibody, hexim1 antibody, Hexim1 antibody, hexim1.L antibody
    背景

    Description: Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor (PubMed:14580347, PubMed:15713661, PubMed:15201869). In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (PubMed:12832472, PubMed:14580347, PubMed:15713661, PubMed:15201869). May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity (PubMed:15940264, PubMed:15941832, PubMed:17088550). Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway (PubMed:28712728).

    Gene: HEXIM1

    分子量
    40kDa
    基因ID
    10614
    UniProt
    O94992
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