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HEXIM1 抗体

HEXIM1 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1944936
发货至: 中国
  • 抗原 See all HEXIM1 抗体
    HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))
    适用
    • 67
    • 54
    • 29
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 64
    • 7
    • 1
    • 1
    克隆类型
    • 68
    • 5
    多克隆
    标记
    • 41
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HEXIM1 antibody is un-conjugated
    应用范围
    • 69
    • 35
    • 33
    • 13
    • 12
    • 11
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    亚型
    IgG
    Top Product
    Discover our top product HEXIM1 Primary Antibody
  • 应用备注
    IF: 1:100. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    储存条件
    4 °C,-20 °C
  • Wittmann, Wang, Montano: "Identification of a novel inhibitor of breast cell growth that is down-regulated by estrogens and decreased in breast tumors." in: Cancer research, Vol. 63, Issue 16, pp. 5151-8, (2003) (PubMed).

    Ouchida, Kusuhara, Shimizu, Hisada, Makino, Morimoto, Handa, Ohsuzu, Tanaka: "Suppression of NF-kappaB-dependent gene expression by a hexamethylene bisacetamide-inducible protein HEXIM1 in human vascular smooth muscle cells." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 8, Issue 2, pp. 95-107, (2003) (PubMed).

    Yik, Chen, Nishimura, Jennings, Link, Zhou: "Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA." in: Molecular cell, Vol. 12, Issue 4, pp. 971-82, (2003) (PubMed).

  • 抗原
    HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))
    别名
    HEXIM1 (HEXIM1 产品)
    别名
    HEXIM1 antibody, fd44h02 antibody, hexim antibody, wu:fd44h02 antibody, zgc:162976 antibody, CLP1 antibody, EDG1 antibody, HIS1 antibody, MAQ1 antibody, 7330426E13Rik antibody, CLP-1 antibody, Clp1 antibody, Clp-1 antibody, hexamethylene bisacetamide inducible 1 antibody, hexamethylene bis-acetamide inducible 1 antibody, hexamethylene bis-acetamide inducible 1 L homeolog antibody, HEXIM1 antibody, hexim1 antibody, Hexim1 antibody, hexim1.L antibody
    背景
    Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.
    分子量
    40623 Da
    基因ID
    10614
    UniProt
    O94992
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