RAD23B 抗体 (AA 125-175)
Quick Overview for RAD23B 抗体 (AA 125-175) (ABIN7454444)
抗原
See all RAD23B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 125-175
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原理
- Rabbit anti-RAD23B Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 125 and 175
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亚型
- IgG
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应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-RAD23B antibody A302-306A.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- RAD23B (RAD23 Homolog B (RAD23B))
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别名
- RAD23B
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背景
- Background: RAD23B is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. RAD23B was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
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基因ID
- 5887
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NCBI登录号
- NP_002865
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UniProt
- P54727
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途径
- DNA Damage Repair
抗原
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