MSK2 抗体 (AA 722-772)
Quick Overview for MSK2 抗体 (AA 722-772) (ABIN7453734)
抗原
See all MSK2 (RPS6KA4) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 722-772
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原理
- Rabbit anti-MSK2 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 722 and 772
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亚型
- IgG
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应用备注
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- MSK2 (RPS6KA4) (Ribosomal Protein S6 Kinase A4 (RPS6KA4))
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别名
- MSK2
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背景
- Background: MSK1 is a serine/threonine kinase required for the mitogen or stress-induced phosphorylation of the transcription factors CREB (cAMP response element-binding protein) and ATF1 (activating transcription factor-1). MSK1 Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A. MSK1 also phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and epidemal growth-factor (EGF), which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN. [taken from the Universal Protein Resource (UniProt) O75582].
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基因ID
- 8986
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NCBI登录号
- NP_003933
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UniProt
- O75676
抗原
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