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MBD2 抗体 (AA 361-411)

This 兔 多克隆 anti-MBD2 antibody specifically detects MBD2 in WB, IP 和 IHC (fp). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7453726
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MBD2 抗体 (AA 361-411) (ABIN7453726)

抗原

See all MBD2 抗体
MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))

适用

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人, 小鼠

宿主

  • 63
  • 2
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克隆类型

  • 41
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多克隆

标记

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This MBD2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

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    AA 361-411

    原理

    Rabbit anti-MBD2 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 361 and 411

    亚型

    IgG
  • 应用备注

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))

    别名

    MBD2

    背景

    Background: MBD2 (methyl-CpG-binding domain protein 2) binds methylated CpG sites and represses gene transcription. DNA methylation is a common mechanism of gene silencing and is central to the developmental process. Methyl-CpG binding proteins (MBPs) have a high affinity for methylated DNA and are proposed to mediate gene silencing via the recruitment of histone deacetylases and other transcriptional repressors to chromatin.

    基因ID

    8932

    NCBI登录号

    NP_003918

    UniProt

    Q9UBB5

    途径

    Chromatin Binding
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