BCAR1 抗体 (AA 275-325)
Quick Overview for BCAR1 抗体 (AA 275-325) (ABIN7453662)
抗原
See all BCAR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 275-325
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原理
 - Rabbit anti-BCAR1/p130CAS Antibody, Affinity Purified
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纯化方法
 - Affinity Purified
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免疫原
 - between AA 275 and 325
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亚型
 - IgG
 
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应用备注
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
 - 仅限研究用
 
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浓度
 - 200 μg/mL
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缓冲液
 - Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C
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有效期
 - 12 months
 
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- BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))
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别名
 - BCAR1/p130CAS
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背景
 - Background: BCAR1/p130CAS functions as a scaffolding protein for components of various kinase signaling pathways. It is involved in integrin signaling for cell motility as well as netrin signaling for the guidance of commissural axons. Overexpression of BCAR1/p130CAS has been shown to confer antiestrogen resistance in breast cancer cells.
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基因ID
 - 9564
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NCBI登录号
 - NP_055382
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UniProt
 - P56945
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途径
 - EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
 
抗原
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