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BCAR1 抗体 (pTyr410)

BCAR1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7139001
发货至: 中国
  • 抗原 See all BCAR1 抗体
    BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))
    抗原表位
    • 27
    • 21
    • 15
    • 7
    • 7
    • 5
    • 4
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    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    pTyr410
    适用
    • 108
    • 61
    • 50
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 116
    • 8
    • 2
    • 1
    克隆类型
    • 121
    • 6
    多克隆
    标记
    • 60
    • 7
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    • 6
    • 6
    • 6
    • 6
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    • 3
    • 3
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    This BCAR1 antibody is un-conjugated
    应用范围
    • 53
    • 39
    • 39
    • 39
    • 24
    • 23
    • 12
    • 10
    • 9
    • 8
    • 2
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
    免疫原
    Peptide sequence around phosphorylation site of tyrosine 410(G-V-Y(p)-A-V) derived from Human p130 Cas .
    亚型
    IgG
    Top Product
    Discover our top product BCAR1 Primary Antibody
  • 应用备注
    WB:1:500-1:1000, IHC:1:50-1:100,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))
    别名
    BCAR1 (BCAR1 产品)
    别名
    CAS antibody, CAS1 antibody, CASS1 antibody, CRKAS antibody, P130Cas antibody, AI385681 antibody, Cas antibody, Crkas antibody, P130CAS antibody, MGC68466 antibody, cas antibody, p130cas antibody, BCAR1 antibody, fc17f11 antibody, wu:fc17f11 antibody, zgc:175192 antibody, BCAR1, Cas family scaffolding protein antibody, breast cancer anti-estrogen resistance 1 antibody, breast cancer anti-estrogen resistance 1 L homeolog antibody, breast cancer anti-estrogen resistance protein 1 antibody, BCAR1 antibody, Bcar1 antibody, bcar1.L antibody, bcar1 antibody, LOC100435586 antibody
    背景

    Background:

    Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.

    Katarzyna Modzelewska, J. Biol. Chem., Dec 2006, 281: 37527 - 37535.
    Kevin Ogden, Am J Physiol Heart Circ Physiol, Dec 2006, 291: H2857 - H2863.
    Sangkil Nam, Cancer Res., Oct 2005, 65: 9185 - 9189.
    Norikazu Yamana, Mol. Cell. Biol., Sep 2006, 26: 6844 - 6

    Aliases: BCAR 1 antibody, Bcar1 antibody, BCAR1_HUMAN antibody, Breast cancer anti estrogen resistance 1 antibody, Breast cancer anti estrogen resistance 1 protein antibody, Breast cancer anti-estrogen resistance protein 1 antibody, CAS antibody, Cas scaffolding protein family member 1 antibody, CAS1 antibody, Cass1 antibody, Crk associated substrate antibody, Crk associated substrate p130Cas antibody, CRK-associated substrate antibody, CRKAS antibody, FLJ12176 antibody, FLJ45059 antibody, p130cas antibody

    UniProt
    P56945
    途径
    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
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