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SMC1A 抗体 (pSer957)

This 兔 多克隆 anti-SMC1A antibody specifically detects SMC1A in WB, IP 和 IHC (fp). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7453448
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for SMC1A 抗体 (pSer957) (ABIN7453448)

抗原

See all SMC1A 抗体
SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

适用

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人, 小鼠

宿主

  • 136
  • 15
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  • 1

克隆类型

  • 99
  • 57
多克隆

标记

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This SMC1A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 37
    • 16
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    • 8
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    • 3
    • 2
    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer957

    原理

    Rabbit anti-Phospho SMC1 (S957) Antibody, Affinity Purified

    预测反应

    Bovine

    纯化方法

    Affinity Purified

    免疫原

    surrounding serine 957

    亚型

    IgG
  • 应用备注

    IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

    别名

    SMC1

    背景

    Background: Structural maintenance of chromosomes (SMC) proteins are part of the cohesin and condensin multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. The core cohesin complex includes a heterodimer of SMC1 and SMC3 that functions by forming a ring-like structure that holds sister chromatids together. Cohesin is important to sister chromatid separation and segregation during mitosis and meiosis and also plays a role in double-strand break repair by homologous recombination.

    基因ID

    8243

    NCBI登录号

    NP_006297

    UniProt

    Q14683

    途径

    Stem Cell Maintenance
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