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MSH2 抗体 (C-Term)

This anti-MSH2 antibody is a 兔 多克隆 antibody detecting MSH2 in WB, IP 和 IHC (fp). Suitable for 人 和 小鼠.
产品编号 ABIN7453440
发货至: 中国

Quick Overview for MSH2 抗体 (C-Term) (ABIN7453440)

抗原

See all MSH2 抗体
MSH2 (Mismatch Repair Protein 2 (MSH2))

适用

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人, 小鼠

宿主

  • 75
  • 31
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克隆类型

  • 71
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  • 1
多克隆

标记

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This MSH2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
  • 抗原表位

    • 15
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    C-Term

    原理

    Rabbit anti-MSH2 Antibody, Affinity Purified

    纯化方法

    Affinity Purified

    免疫原

    between AA 875 and C-term

    亚型

    IgG
  • 应用备注

    IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    MSH2 (Mismatch Repair Protein 2 (MSH2))

    别名

    MSH2

    背景

    Background: MSH2 is an integral component of the DNA mismatch repair (MMR) system that functions to recognize aberrant structures and signals for the repair of single base mismatches or loops in replicated DNA. MSH2 has also been demonstrated to function as an anti-recombinase and may play a role in negatively regulating DNA repair. MSH2 can heterodimerize with MSH3 or MSH6. Mutations in MSH2 are linked to hereditary nonpolyposis colon cancer (HNPCC).

    基因ID

    4436

    NCBI登录号

    NP_000242

    UniProt

    P43246

    途径

    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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