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CDK6 抗体 (AA 250-300)

The 兔 多克隆 anti-CDK6 antibody (ABIN7453059) specifically detects CDK6 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN7453059
发货至: 中国
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Quick Overview for CDK6 抗体 (AA 250-300) (ABIN7453059)

抗原

See all CDK6 抗体
CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

适用

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宿主

  • 111
  • 17

克隆类型

  • 88
  • 40
多克隆

标记

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This CDK6 antibody is un-conjugated

应用范围

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  • 17
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  • 2
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Western Blotting (WB)
  • 抗原表位

    • 21
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    • 1
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    AA 250-300

    原理

    Rabbit anti-CDK6 Antibody, Affinity Purified

    预测反应

    Mouse

    纯化方法

    Affinity Purified

    免疫原

    Between AA 250 and 300

    亚型

    IgG
  • 应用备注

    IP: Not recommended

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

    别名

    CDK6

    背景

    Background: Cell division protein kinase 6 is a Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation. CDK6 interacts with D-type G1 cyclins during interphase at G1 to form a pRB/RB1 kinase and controls the entrance into the cell cycle. It is involved in initiation and maintenance of cell cycle exit during cell differentiation. Although, it prevents cell proliferation and regulates negatively cell differentiation, it is required for the proliferation of specific cell types (e.g. erythroid and hematopoietic cells). it is also essential for cell proliferation within the dentate gyrus of the hippocampus and the subventricular zone of the lateral ventricles. It may play a role in the centrosome organization during the cell cycle phases (PubMed:23918663) [taken from the Universal Protein Resource (UniProt) Q00534].

    基因ID

    1021

    UniProt

    Q00534

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases
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