CDK6 抗体 (AA 250-300)
Quick Overview for CDK6 抗体 (AA 250-300) (ABIN7453059)
抗原
See all CDK6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 250-300
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原理
- Rabbit anti-CDK6 Antibody, Affinity Purified
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预测反应
- Mouse
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纯化方法
- Affinity Purified
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免疫原
- Between AA 250 and 300
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亚型
- IgG
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应用备注
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IP: Not recommended
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
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别名
- CDK6
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背景
- Background: Cell division protein kinase 6 is a Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation. CDK6 interacts with D-type G1 cyclins during interphase at G1 to form a pRB/RB1 kinase and controls the entrance into the cell cycle. It is involved in initiation and maintenance of cell cycle exit during cell differentiation. Although, it prevents cell proliferation and regulates negatively cell differentiation, it is required for the proliferation of specific cell types (e.g. erythroid and hematopoietic cells). it is also essential for cell proliferation within the dentate gyrus of the hippocampus and the subventricular zone of the lateral ventricles. It may play a role in the centrosome organization during the cell cycle phases (PubMed:23918663) [taken from the Universal Protein Resource (UniProt) Q00534].
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基因ID
- 1021
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UniProt
- Q00534
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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