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CDK6 抗体 (AA 102-326)

CDK6 适用: 人 IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7148898
发货至: 中国
  • 抗原 See all CDK6 抗体
    CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
    抗原表位
    • 22
    • 21
    • 14
    • 11
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 102-326
    适用
    • 127
    • 49
    • 26
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    宿主
    • 110
    • 17
    克隆类型
    • 99
    • 28
    多克隆
    标记
    • 68
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CDK6 antibody is un-conjugated
    应用范围
    • 77
    • 37
    • 29
    • 27
    • 27
    • 23
    • 23
    • 13
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Cyclin-dependent kinase 6 protein (102-326AA)
    亚型
    IgG
    Top Product
    Discover our top product CDK6 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:200-1:500, IF:1:100-1:500,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
    别名
    CDK6 (CDK6 产品)
    别名
    CDK6 antibody, PLSTIRE antibody, 5830411I20 antibody, AI504062 antibody, Crk2 antibody, cyclin dependent kinase 6 antibody, cyclin-dependent kinase 6 antibody, CDK6 antibody, Cdk6 antibody
    背景

    Background: Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation, promotes G1/S transition. Phosphorylates pRB/RB1 and NPM1. Interacts with D-type G1 cyclins during interphase at G1 to form a pRB/RB1 kinase and controls the entrance into the cell cycle. Involved in initiation and maintenance of cell cycle exit during cell differentiation, prevents cell proliferation and regulates negatively cell differentiation, but is required for the proliferation of specific cell types (e.g. erythroid and hematopoietic cells). Essential for cell proliferation within the dentate gyrus of the hippocampus and the subventricular zone of the lateral ventricles. Required during thymocyte development. Promotes the production of newborn neurons, probably by modulating G1 length. Promotes, at least in astrocytes, changes in patterns of gene expression, changes in the actin cytoskeleton including loss of stress fibers, and enhanced motility during cell differentiation. Prevents myeloid differentiation by interfering with RUNX1 and reducing its transcription transactivation activity, but promotes proliferation of normal myeloid progenitors. Delays senescence. Promotes the proliferation of beta-cells in pancreatic islets of Langerhans. May play a role in the centrosome organization during the cell cycle phases (PubMed:23918663).

    Aliases: CDK 6 antibody, CDK6 antibody, CDK6_HUMAN antibody, Cell division protein kinase 6 antibody, Crk 2 antibody, Crk2 antibody, Cyclin dependent kinase 6 antibody, Cyclin-dependent kinase 6 antibody, MCPH12 antibody, MGC59692 antibody, p40 antibody, PLSTIRE antibody, Serine/threonine protein kinase PLSTIRE antibody, Serine/threonine-protein kinase PLSTIRE antibody, STQTL11 antibody

    UniProt
    Q00534
    途径
    Cell Division Cycle, Mitotic G1-G1/S Phases
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