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Notch1 抗体 (AA 2400-2450)

This anti-Notch1 antibody is a 兔 多克隆 antibody detecting Notch1 in IP. Suitable for 人.
产品编号 ABIN7452378
发货至: 中国

Quick Overview for Notch1 抗体 (AA 2400-2450) (ABIN7452378)

抗原

See all Notch1 (NOTCH1) 抗体
Notch1 (NOTCH1) (Notch 1 (NOTCH1))

适用

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宿主

  • 106
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克隆类型

  • 97
  • 59
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多克隆

标记

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This Notch1 antibody is un-conjugated

应用范围

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Immunoprecipitation (IP)
  • 抗原表位

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    • 1
    • 1
    • 1
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    AA 2400-2450

    原理

    Rabbit anti-Notch1 Antibody, Affinity Purified

    预测反应

    Mouse,Rat

    纯化方法

    Affinity Purified

    免疫原

    between AA 2400 and 2450

    亚型

    IgG
  • 应用备注

    IP: 2 - 5 μg/mg lysate

    WB: Not recommended. Use rabbit anti-Notch1 antibody A301-895A.

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    Notch1 (NOTCH1) (Notch 1 (NOTCH1))

    别名

    Notch1

    背景

    Background: Notch1 is the human homolog of the D. melanogaster Notch gene first reported as the gene responsible for the presence of notches in the wingblades of a specific strain of flies. The Notch protein is a transmembrane receptor that mediates juxtacrine signals between adjacent cells. Mammalian Notch1 ligands include Delta-like and Jagged. Upon ligand binding, Notch1 undergoes two proteolytic cleavage events that result in the release of the intracellular Notch1 domain and its translocation to the nucleus where it can participate in gene transactivation. Notch 1 signals mediate cellular fate, differentiation, and development.

    基因ID

    4851

    NCBI登录号

    NP_060087

    UniProt

    P46531

    途径

    Notch Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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