Notch1 抗体 (AA 2400-2450)
Quick Overview for Notch1 抗体 (AA 2400-2450) (ABIN7452378)
抗原
See all Notch1 (NOTCH1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2400-2450
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原理
- Rabbit anti-Notch1 Antibody, Affinity Purified
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预测反应
- Mouse,Rat
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纯化方法
- Affinity Purified
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免疫原
- between AA 2400 and 2450
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-Notch1 antibody A301-895A.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- Notch1 (NOTCH1) (Notch 1 (NOTCH1))
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别名
- Notch1
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背景
- Background: Notch1 is the human homolog of the D. melanogaster Notch gene first reported as the gene responsible for the presence of notches in the wingblades of a specific strain of flies. The Notch protein is a transmembrane receptor that mediates juxtacrine signals between adjacent cells. Mammalian Notch1 ligands include Delta-like and Jagged. Upon ligand binding, Notch1 undergoes two proteolytic cleavage events that result in the release of the intracellular Notch1 domain and its translocation to the nucleus where it can participate in gene transactivation. Notch 1 signals mediate cellular fate, differentiation, and development.
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基因ID
- 4851
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NCBI登录号
- NP_060087
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UniProt
- P46531
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途径
- Notch Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
抗原
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