PAK2 抗体 (AA 25-75)
Quick Overview for PAK2 抗体 (AA 25-75) (ABIN7451932)
抗原
See all PAK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-75
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原理
- Rabbit anti-PAK2 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 25 and 75
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亚型
- IgG
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PAK2 (P21-Activated Kinase 2 (PAK2))
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别名
- PAK2
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背景
- Background: PAK2 (p21-activated kinase 2) is part of the family of PAK serine/threonine p21-activating protein kinases involved in cell survival, migration, and invasion. The PAK family of proteins mediates signals from extracellular stimuli to the cytoplasm and nucleus via its association with the small GTP-binding proteins Cdc42 and Rac. PAK2 has been shown to play a specific role in apoptosis and cytoskeletal dynamics. During caspase-mediated apoptosis, PAK2 is cleaved and the C-terminal myristoylated fragment mediates cell death and actin reorganization via the JNK signaling pathway.
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基因ID
- 5062
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NCBI登录号
- NP_002568
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UniProt
- Q13177
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途径
- MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
抗原
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