FIP200 抗体 (AA 1544-1594)
Quick Overview for FIP200 抗体 (AA 1544-1594) (ABIN7451783)
抗原
See all FIP200 (RB1CC1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1544-1594
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原理
- Rabbit anti-FIP200/RB1CC1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 1544 and 1594
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亚型
- IgG
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anti-RB1-Inducible Coiled-Coil 1 (RB1CC1) (AA 501-600) antibody
RB1CC1 适用: 小鸡 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-RB1-Inducible Coiled-Coil 1 (RB1CC1) (C-Term) antibodyRB1CC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-RB1-Inducible Coiled-Coil 1 (RB1CC1) (AA 148-244) antibodyRB1CC1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2C9A11 unconjugated
anti-RB1-Inducible Coiled-Coil 1 (RB1CC1) (AA 1544-1594) antibodyRB1CC1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-RB1-Inducible Coiled-Coil 1 (RB1CC1) (C-Term) antibodyRB1CC1 适用: 人, 小鼠, 小鸡, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-RB1-Inducible Coiled-Coil 1 (RB1CC1) (C-Term) antibodyRB1CC1 适用: 人, 小鼠, 小鸡, 大鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-RB1-Inducible Coiled-Coil 1 (RB1CC1) (C-Term) antibodyRB1CC1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))
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别名
- FIP200/RB1CC1
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背景
- Background: FIP200 (FAK-family interacting protein of 200 kDa) appears to play several key roles related to cell growth, proliferation, development, and tumorigenesis. FIP200 was originally identified in a yeast two-hybrid screen for Pyk2 kinase interacting proteins. It was later identified as a protein that interacts with FAK (focal adhesion kinase), a signal transducing protein that mediates signals from the extracellular matrix to the cytoskeleton to influence cell motility, and cell cycle progression. FIP200 is also known as RB1CC1 (RB1-inducible coiled-coil 1) and has been found to function as a regulator of the retinoblastoma 1 (RB1) tumor suppressor. FIP200 associates with the tumor suppressor TSC1 which partners with TSC2 to antagonize the mTOR signaling pathway. FIP200 association with TSC2 promotes mTOR activity by interfering with the antagonistic effects of the TSC1-TSC2 complex.
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基因ID
- 9821
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NCBI登录号
- NP_055596
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UniProt
- Q8TDY2
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途径
- Regulation of Cell Size, Autophagy
抗原
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