电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

ERBB3 抗体 (AA 1275-1325)

This anti-ERBB3 antibody is a 兔 多克隆 antibody detecting ERBB3 in IP. Suitable for 人.
产品编号 ABIN7451238
发货至: 中国

Quick Overview for ERBB3 抗体 (AA 1275-1325) (ABIN7451238)

抗原

See all ERBB3 抗体
ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

适用

  • 164
  • 104
  • 89
  • 17
  • 6
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 171
  • 28
  • 1
  • 1

克隆类型

  • 162
  • 39
多克隆

标记

  • 112
  • 15
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
This ERBB3 antibody is un-conjugated

应用范围

  • 105
  • 72
  • 53
  • 53
  • 53
  • 31
  • 29
  • 20
  • 20
  • 15
  • 11
  • 3
  • 3
  • 3
  • 2
  • 1
Immunoprecipitation (IP)
  • 抗原表位

    • 27
    • 26
    • 15
    • 15
    • 14
    • 9
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1275-1325

    原理

    Rabbit anti-ErbB3 Antibody, Affinity Purified

    预测反应

    Orangutan

    纯化方法

    Affinity Purified

    免疫原

    Between AA 1275 and 1325

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: Not recommended. Use rabbit anti-ErbB3 antibody ABIN7449726.

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

    别名

    ErbB3

    背景

    Background: ErbB3, also known as HER3, is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors[taken from NCBI Entrez Gene (Gene ID: 2065)].

    基因ID

    2065

    NCBI登录号

    NP_001973

    UniProt

    P21860

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
You are here:
Chat with us!