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SYK 抗体 (AA 350-400)

This 兔 多克隆 anti-SYK antibody specifically detects SYK in WB 和 IP. The antibody is reactive with 人 samples.
产品编号 ABIN7450791
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SYK 抗体 (AA 350-400) (ABIN7450791)

抗原

See all SYK 抗体
SYK (Spleen tyrosine Kinase (SYK))

适用

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宿主

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克隆类型

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多克隆

标记

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This SYK antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
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    AA 350-400

    原理

    Rabbit anti-SYK Antibody, Affinity Purified

    预测反应

    Mouse,Rat,Pig

    纯化方法

    Affinity Purified

    免疫原

    between AA 350 and 400

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    SYK (Spleen tyrosine Kinase (SYK))

    别名

    SYK

    背景

    Background: SYK (spleen tyrosine kinase) is a ubiquitously expressed tyrosine kinase that functions in mediating B and T-cell receptor signaling and is also important to various aspects of leukocyte function that involve cytoskeleton remodeling. In mediating hematopoietic cell signaling, SYK is a substrate of src family kinase activity and is a key-regulator of Akt kinase activity. SYK has also been found to be highly expressed in the mammary gland and has been shown to inhibit tumor growth and metastasis. Invasive breast tumor cell lines have been shown to exhibit reduced or absent levels of SYK, further implicating a role in tumorigenesis and metastasis.

    基因ID

    6850

    NCBI登录号

    NP_003168

    UniProt

    P43405

    途径

    Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
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