Septin 2 抗体 (AA 275-325)
Quick Overview for Septin 2 抗体 (AA 275-325) (ABIN7450720)
抗原
See all Septin 2 (SEPT2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 275-325
-
原理
- Rabbit anti-Septin 2 Antibody, Affinity Purified
-
预测反应
- Rat,Bovine,Orangutan
-
纯化方法
- Affinity Purified
-
免疫原
- Between AA 275 and 325
-
亚型
- IgG
-
-
-
-
应用备注
-
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
-
限制
- 仅限研究用
-
-
-
浓度
- 1000 μg/mL
-
缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- Septin 2 (SEPT2)
-
别名
- Septin 2
-
背景
- Background: Septin 2 is a filament-forming cytoskeletal GTPase. Septin 2 is required for normal organization of the actin cytoskeleton and plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. It is required for the progression through mitosis, and it forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, Septin 2 may be required for chromosome segregation and spindle elongation. Septin 2 also plays a role in ciliogenesis and collective cell movements [taken from the Universal Protein Resource (UniProt) Q15019].
-
基因ID
- 4735
-
NCBI登录号
- NP_001008491
-
UniProt
- Q15019
抗原
-