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PKC theta 抗体 (AA 656-706)

This anti-PKC theta antibody is a 兔 多克隆 antibody detecting PKC theta in WB 和 IP. Suitable for 人.
产品编号 ABIN7450605
发货至: 中国

Quick Overview for PKC theta 抗体 (AA 656-706) (ABIN7450605)

抗原

See all PKC theta (PRKCQ) 抗体
PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))

适用

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宿主

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克隆类型

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多克隆

标记

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This PKC theta antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

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    AA 656-706

    原理

    Rabbit anti-PRKCQ Antibody, Affinity Purified

    预测反应

    Mouse,Rat

    纯化方法

    Affinity Purified

    免疫原

    Between AA 656 and 706

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))

    别名

    PRKCQ

    背景

    Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. Protein kinase C theta type (PRKCQ) is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factor [taken from NCBI Entrez Gene (Gene ID: 5588)].

    基因ID

    5588

    NCBI登录号

    NP_006248

    UniProt

    Q04759

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
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