PKC theta 抗体 (AA 350-400)
Quick Overview for PKC theta 抗体 (AA 350-400) (ABIN7450604)
抗原
See all PKC theta (PRKCQ) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 350-400
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原理
- Rabbit anti-PRKCQ Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 350 and 400
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- PKC theta (PRKCQ) (Protein Kinase C, theta (PRKCQ))
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别名
- PRKCQ
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背景
- Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. Protein kinase C theta type (PRKCQ) is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factor [taken from NCBI Entrez Gene (Gene ID: 5588)].
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基因ID
- 5588
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NCBI登录号
- NP_006248
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UniProt
- Q04759
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling
抗原
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