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PARN 抗体 (AA 539-589)

This anti-PARN antibody is a 兔 多克隆 antibody detecting PARN in WB 和 IP. Suitable for 人.
产品编号 ABIN7450543
发货至: 中国

Quick Overview for PARN 抗体 (AA 539-589) (ABIN7450543)

抗原

See all PARN 抗体
PARN (Poly A Specific Ribonuclease (PARN))

适用

  • 43
  • 9
  • 7
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 32
  • 11

克隆类型

  • 35
  • 8
多克隆

标记

  • 31
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PARN antibody is un-conjugated

应用范围

  • 33
  • 18
  • 13
  • 11
  • 8
  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 539-589

    原理

    Rabbit anti-PARN Antibody, Affinity Purified

    预测反应

    Orangutan

    纯化方法

    Affinity Purified

    免疫原

    between AA 539 and 589

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    PARN (Poly A Specific Ribonuclease (PARN))

    别名

    PARN

    背景

    Background: Poly(A)-specific ribonuclease (PARN) is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. PARN prefers poly(A) as the substrate, hence, it efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. PARN is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons [taken from NCBI Entrez Gene (Gene ID: 5073)].

    基因ID

    5073

    NCBI登录号

    NP_002573

    UniProt

    O95453
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