PAK4 抗体 (AA 25-75)
Quick Overview for PAK4 抗体 (AA 25-75) (ABIN7450536)
抗原
See all PAK4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 25-75
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原理
 - Rabbit anti-PAK4 Antibody, Affinity Purified
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纯化方法
 - Affinity Purified
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免疫原
 - between AA 25 and 75
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亚型
 - IgG
 
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
 - 仅限研究用
 
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浓度
 - 1000 μg/mL
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缓冲液
 - Phosphate Buffered Saline (PBS) containing 0.09 % Sodium Azide
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C
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有效期
 - 12 months
 
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- PAK4 (P21-Activated Kinase 4 (PAK4))
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别名
 - PAK4
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背景
 - Background: PAK4 is a member of the PAK family of serine/threonine p21-activating kinases. PAK4 is a target for the GTP-bound Rho GTPase, CDC42, and is an important factor that links Rho GTPases such as Ras to transformation. In this context, PAK4 is highly transforming, and has been found to be highly expressed in some tumor cell lines. PAK4 has been demonstrated to activate the JNK pathway and mediate the formation of filopodia and the reorganization of the actin cytoskeleton. PAK4 has also been found to function as a regulator of prosurvival pathways and senescence.
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基因ID
 - 10298
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NCBI登录号
 - NP_005875
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UniProt
 - O96013
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途径
 - RTK signaling
 
抗原
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