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NBR1 抗体 (AA 916-966)

This 兔 多克隆 anti-NBR1 antibody specifically detects NBR1 in WB 和 IP. The antibody is reactive with 人 samples.
产品编号 ABIN7450479
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for NBR1 抗体 (AA 916-966) (ABIN7450479)

抗原

See all NBR1 抗体
NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

适用

  • 27
  • 9
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  • 1
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宿主

  • 15
  • 14

克隆类型

  • 17
  • 12
多克隆

标记

  • 23
  • 2
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  • 2
This NBR1 antibody is un-conjugated

应用范围

  • 24
  • 12
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Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 916-966

    原理

    Rabbit anti-NBR1 Antibody, Affinity Purified

    预测反应

    Orangutan

    纯化方法

    Affinity Purified

    免疫原

    Between AA 916 and 966

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

    别名

    NBR1

    背景

    Background: NBR1 (Next to BRCA1 gene 1 protein) was originally identified as an ovarian tumor antigen monitored in ovarian cancer.NBR1 contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. The gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene [taken from NCBI Entrez Gene (Gene ID: 4077)].

    基因ID

    4077

    UniProt

    Q14596

    途径

    Autophagy
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