NBR1 抗体 (AA 916-966)
Quick Overview for NBR1 抗体 (AA 916-966) (ABIN7450479)
抗原
See all NBR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 916-966
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原理
- Rabbit anti-NBR1 Antibody, Affinity Purified
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预测反应
- Orangutan
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纯化方法
- Affinity Purified
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免疫原
- Between AA 916 and 966
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))
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别名
- NBR1
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背景
- Background: NBR1 (Next to BRCA1 gene 1 protein) was originally identified as an ovarian tumor antigen monitored in ovarian cancer.NBR1 contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. The gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene [taken from NCBI Entrez Gene (Gene ID: 4077)].
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基因ID
- 4077
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UniProt
- Q14596
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途径
- Autophagy
抗原
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