MTOR 抗体 (AA 200-250)
Quick Overview for MTOR 抗体 (AA 200-250) (ABIN7450467)
抗原
See all MTOR (mTOR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 200-250
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原理
- Rabbit anti-mTOR Antibody, Affinity Purified
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预测反应
- Mouse,Rat
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纯化方法
- Affinity Purified
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免疫原
- between AA 200 and 250
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))
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别名
- mTOR
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背景
- Background: Studies of the mammalian target of rapamycin (mTOR) and its homologs demonstrate a role in integrating signals from growth factors, nutrients, stress, and cellular energy levels to control cell growth, translation initiation, ribosome biogenesis, and transcription factor localization. mTOR is the direct target of the cell cycle arresting activity of rapamycin. mTOR interacts with Raptor or Rictor to form the mTORC1 and mTORC2 complexes respectively. The mTORC1 complex also includes mLst8/GbetaL and functions to phosphorylate S6K and 4EBP1. The mTORC2 complex also includes mLst8/GbetaL, mSIN1 and protor-1 and functions to phosphorylate Akt.
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基因ID
- 2475
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NCBI登录号
- NP_004949
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UniProt
- P42345
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途径
- PI3K-Akt Signaling, RTK signaling, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effect
抗原
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