DYRK1A 抗体 (AA 713-763)
Quick Overview for DYRK1A 抗体 (AA 713-763) (ABIN7450193)
抗原
See all DYRK1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 713-763
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原理
- Rabbit anti-DYRK1A Antibody, Affinity Purified
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预测反应
- Mouse,Rat,X. laevis,X. tropicalis
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纯化方法
- Affinity Purified
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免疫原
- Between AA 713 and 763
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
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别名
- DYRK1A
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背景
- Background: Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A) a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. DYRK1A contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. DYRK1A may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. The DYRK1A gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome [taken from NCBI Entrez Gene (Gene ID: 5201)].
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基因ID
- 1859
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NCBI登录号
- NP_001387
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UniProt
- Q13627
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途径
- Mitotic G1-G1/S Phases
抗原
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