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Cullin 1 抗体 (AA 726-776)

This 兔 多克隆 antibody specifically detects Cullin 1 in WB 和 IP. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN7450144
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for Cullin 1 抗体 (AA 726-776) (ABIN7450144)

抗原

See all Cullin 1 (CUL1) 抗体
Cullin 1 (CUL1)

适用

  • 93
  • 52
  • 47
  • 7
  • 6
  • 5
  • 5
  • 5
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 92
  • 1

克隆类型

  • 62
  • 31
多克隆

标记

  • 42
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Cullin 1 antibody is un-conjugated

应用范围

  • 59
  • 36
  • 28
  • 22
  • 18
  • 13
  • 13
  • 9
  • 8
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

    • 15
    • 12
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 726-776

    原理

    Rabbit anti-Cul1 Antibody, Affinity Purified

    预测反应

    Orangutan

    纯化方法

    Affinity Purified

    免疫原

    between AA 726 and 776

    亚型

    IgG
  • 应用备注

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    Cullin 1 (CUL1)

    别名

    Cul1

    背景

    Background: Cullin 1 (Cul1) is the core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, Cul1 serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. Cul1 may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme [taken from the Universal Protein Resource (UniProt) Q13616].

    基因ID

    8454

    NCBI登录号

    NP_003583

    UniProt

    Q13616

    途径

    Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases, Regulation of Cell Size
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