MSH2 抗体 (AA 1-50)
Quick Overview for MSH2 抗体 (AA 1-50) (ABIN7449896)
抗原
See all MSH2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-50
-
原理
- Rabbit anti-MSH2 Antibody, Affinity Purified
-
纯化方法
- Affinity Purified
-
免疫原
- between AA 1 and 50
-
亚型
- IgG
-
-
-
-
应用备注
-
IP: 2 - 10 μg/mg lysate
WB: 1:10,000 - 1:25,000
-
限制
- 仅限研究用
-
-
-
浓度
- 1000 μg/mL
-
缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- MSH2 (Mismatch Repair Protein 2 (MSH2))
-
别名
- MSH2
-
背景
- Background: MSH2 is an integral component of the DNA mismatch repair (MMR) system that functions to recognize aberrant structures and signals for the repair of single base mismatches or loops in replicated DNA. MSH2 has also been demonstrated to function as an anti-recombinase and may play a role in negatively regulating DNA repair. MSH2 can heterodimerize with MSH3 or MSH6. Mutations in MSH2 are linked to hereditary nonpolyposis colon cancer (HNPCC).
-
基因ID
- 4436
-
NCBI登录号
- NP_000242
-
UniProt
- P43246
-
途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
-