MAML1 抗体 (AA 75-125)
Quick Overview for MAML1 抗体 (AA 75-125) (ABIN7449893)
抗原
See all MAML1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 75-125
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原理
- Rabbit anti-MAML1 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 75 and 125
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:10,000 - 1:25,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- MAML1 (Mastermind-Like 1 (MAML1))
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别名
- MAML1
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背景
- Background: There are 3 MAML (mastermind-like) proteins in mammals (MAML1-3). MAML1 is a critical coactivator for NOTCH signaling. MAML1 associates with NOTCH and CSL in a ternary complex and functions to activate transcription of HES and hairy-related basic helix-loop-helix transcription factors. MAML1 has been observed to interact with p300 to acetylate histones H3 and H4. MAML1 also interacts with p53 and functions independent of NOTCH signaling, as a coactivator of p53 target genes.
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基因ID
- 9794
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NCBI登录号
- NP_055572
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UniProt
- Q92585
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途径
- Notch Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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