BRCA2 抗体 (AA 450-500)
Quick Overview for BRCA2 抗体 (AA 450-500) (ABIN7449874)
抗原
See all BRCA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 450-500
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原理
- Rabbit anti-BRCA2 Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 450 and 500
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:10,000 - 1:25,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- BRCA2 (Breast Cancer 2, Early Onset (BRCA2))
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别名
- BRCA2
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背景
- Background: BRCA2 was identified as a gene with germline mutations that predisposes women to breast cancer. An important function of BRCA2 involves its direct interaction with RAD51 and the process of homologous recombination in DNA double strand break repair. BRCA2 and BRCA1 primary sequences are not similar, however the proteins exhibit similar patterns of expression and sub-cellular localization. Although the phenotype of disruptions of BRCA2 is similar to BRCA1, BRCA2 appears to possess functions distinct from BRCA1.
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基因ID
- 675
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NCBI登录号
- NP_000050
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UniProt
- P51587
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途径
- DNA Damage Repair, M Phase, Maintenance of Protein Location
抗原
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