SETMAR 抗体 (AA 1-50)
Quick Overview for SETMAR 抗体 (AA 1-50) (ABIN7449766)
抗原
See all SETMAR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-50
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原理
- Rabbit anti-Metnase Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- Between AA 1 and 50
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亚型
- IgG
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应用备注
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IP: 2 - 10 μg/mg lysate
WB: 1:1,000 - 1:5,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
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别名
- Metnase
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背景
- Background: Metnase is also known as Histone-lysine N-methyltransferase SETMAR. Metnase is a histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3, 2 specific tags for epigenetic transcriptional activation. Metanase specifically mediates dimethylation of H3 'Lys-36', and has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element. Metnase possessess DNA nicking activity and in vivo end joining activity, and it may mediate genomic integration of foreign DNA [taken from the Universal Protein Resource (UniProt) Q53H47].
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基因ID
- 6419
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UniProt
- Q53H47
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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