SETMAR 抗体 (Internal Region)
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Quick Overview for SETMAR 抗体 (Internal Region) (ABIN7224234)
抗原
See all SETMAR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- Rabbit Anti-SETMAR Polyclonal Antibody
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特异性
- SETMAR Polyclonal Antibody detects endogenous levels of SETMAR protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human SETMAR
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
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别名
- SETMAR
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背景
- SETMAR, Histone-lysine N-methyltransferase SETMAR, SET domain and mariner transposase fusion gene-containing protein, HsMar1, MetnaseSETMAR (SET domain and mariner transposase fusion gene) encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. SETMAR exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
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基因ID
- 6419
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UniProt
- Q53H47
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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