BLM 抗体 (AA 1-50)
Quick Overview for BLM 抗体 (AA 1-50) (ABIN7449605)
抗原
See all BLM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-50
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原理
- Rabbit anti-BLM Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 1 and 50
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亚型
- IgG
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应用备注
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IP: 1 - 4 μg/mg lysate
WB: Not recommended. Use rabbit anti-BLM antibody ABIN7450035 for WB of mouse BLM.
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- BLM (Bloom Syndrome RecQ Like Helicase (BLM))
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别名
- BLM
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背景
- Background: Bloom syndrome protein (BLM) is a RecQ DNA-helicase that plays a role in DNA replication and repair. Mutations and inactivation of BLM result in human syndromes characterized by dwarfism, infertility, erythema, learning disabilities, immune deficiency and predisposition to cancer. BLM has been shown to associate with the BRCA1-associated genome surveillance complex (BASC) which contains BRCA1, MSH2, MSH6, MLH1, ATM, PMS2 and the RAD50-MRE11-NBS1 protein complex.
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基因ID
- 12144
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NCBI登录号
- NP_031576
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UniProt
- O88700
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途径
- DNA Damage Repair
抗原
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