ube3a 抗体 (AA 75-125)
Quick Overview for ube3a 抗体 (AA 75-125) (ABIN7449574)
抗原
See all ube3a 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 75-125
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原理
- Rabbit anti-E6AP Antibody, Affinity Purified
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纯化方法
- Affinity Purified
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免疫原
- between AA 75 and 125
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亚型
- IgG
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应用备注
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IP: 1 - 4 μg/mg lysate
WB: 1:1,000 - 1:5,000
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限制
- 仅限研究用
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浓度
- 1000 μg/mL
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缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- ube3a (Ubiquitin Protein Ligase E3A (ube3a))
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别名
- E6AP
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背景
- Background: E6AP is an E3 ubiquitin ligase. Inheritance of a mutant maternal copy of this gene results in Angelman syndrome (AS) which is characterized by severe mental retardation, seizures, ataxia, and EEG abnormalities. E6AP interacts with the type 16 and 18 human papillomavirus E6 oncoprotein which results in the targeting of p53 for degradation via the ubiquitin-proteasome system.
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基因ID
- 7337
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NCBI登录号
- NP_000453
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UniProt
- Q05086
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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