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HLA-DR 抗体

The 小鼠 单克隆 anti-HLA-DR antibody (Clone LN3) (ABIN7449537) specifically detects HLA-DR in FACS, WB, IHC, ICC 和 IF (p). The antibody is reactive with 人 samples.
产品编号 ABIN7449537
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HLA-DR 抗体 (ABIN7449537)

抗原

HLA-DR

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This HLA-DR antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

克隆位点

LN3
  • 原理

    Mouse anti-HLA-DR Monoclonal Antibody Purified [LN3]

    纯化方法

    Purified

    免疫原

    Activated human peripheral blood mononuclear cells

    亚型

    IgG2b
  • 应用备注

    IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    WB: 17:40:00

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    50 μg/mL

    缓冲液

    Phosphate Buffered Saline (PBS) with 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2 - 8 °C

    有效期

    12 months
  • 抗原

    HLA-DR

    别名

    HLA-DR

    背景

    In humans, Major Histocompatibility Locus (MHC) class II molecules are encoded by three different loci, HLA-DR, -DQ, and -DP, which display ~70 % similarity to each other. Polymorphism is a notable feature of MHC class II genes. HLA-DR, HLA-DP, and HLA-DQ are heterodimeric cell surface glycoproteins comprised of an α (heavy) chain and a β (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 Molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. Variations in the HLA gene expression are crucial to graft survival.

    基因ID

    3122

    UniProt

    P01903

    途径

    Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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