RAD50 抗体 (AA 700-750)
Quick Overview for RAD50 抗体 (AA 700-750) (ABIN7449388)
抗原
See all RAD50 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 700-750
-
原理
- Rabbit anti-Rad50 Antibody, Affinity Purified
-
预测反应
- Bovine,Dog,Rabbit,Orangutan,Monkey,Gorilla,Chimpanzee
-
纯化方法
- Affinity Purified
-
免疫原
- between AA 700 and 750
-
亚型
- IgG
-
-
-
-
应用备注
-
IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
WB: 1:1,000 - 1:5,000
-
限制
- 仅限研究用
-
-
-
浓度
- 1000 μg/mL
-
缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
有效期
- 12 months
-
-
- RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
-
别名
- Rad50
-
背景
- Background: Rad50 is a component of the Mre11-Rad50-Nbs1 (MRN) complex that repairs DNA double strand breaks during DNA damage and homologous recombination and activates the S-phase checkpoint. Rad50 shows structural similarity to the structural maintenance of chromosomes (SMC) family of proteins. Rad50 has been shown to directly interact with BRCA2, TERF2IP, and ATM.
-
基因ID
- 10111
-
NCBI登录号
- NP_005723
-
UniProt
- Q92878
-
途径
- DNA Damage Repair, Protein targeting to Nucleus
抗原
-