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BRCA1 抗体 (pSer1524)

This anti-BRCA1 antibody is a 兔 多克隆 antibody detecting BRCA1 in WB. Suitable for 人.
产品编号 ABIN7449280
发货至: 中国

Quick Overview for BRCA1 抗体 (pSer1524) (ABIN7449280)

抗原

See all BRCA1 抗体
BRCA1 (Breast Cancer 1 (BRCA1))

适用

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宿主

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克隆类型

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多克隆

标记

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This BRCA1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    pSer1524

    原理

    Rabbit anti-Phospho BRCA1 (S1524) Antibody, Affinity Purified

    预测反应

    Gorilla,Chimpanzee

    纯化方法

    Affinity Purified

    免疫原

    surrounding serine 1524

    亚型

    IgG
  • 应用备注

    1:500 - 1:5,000

    限制

    仅限研究用
  • 浓度

    1000 μg/mL

    缓冲液

    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    BRCA1 (Breast Cancer 1 (BRCA1))

    别名

    BRCA1

    背景

    Background: BRCA1 was identified as a gene with germline mutations that predisposes women to breast and ovarian cancer. The BRCA1 tumor suppressor is a large protein that has been demonstrated to interact with a multitude of proteins involved in the DNA damage response and cell cycle checkpoints to maintain genomic integrity. BRCA1 functions by regulating the activities of its interacting proteins which mediate processes such as gene transcription, gene repression, protein phosphorylation, and ubiquitination.

    基因ID

    672

    NCBI登录号

    NP_009225

    UniProt

    P38398

    途径

    Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus
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