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14-3-3 sigma/SFN 抗体 (AA 198-248)

This anti-14-3-3 sigma/SFN antibody is a 兔 多克隆 antibody detecting 14-3-3 sigma/SFN in IHC 和 IF (p). Suitable for 人.
产品编号 ABIN7448925
发货至: 中国

Quick Overview for 14-3-3 sigma/SFN 抗体 (AA 198-248) (ABIN7448925)

抗原

See all 14-3-3 sigma/SFN (SFN) 抗体
14-3-3 sigma/SFN (SFN) (Stratifin (SFN))

适用

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宿主

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克隆类型

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多克隆

标记

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This 14-3-3 sigma/SFN antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 198-248

    原理

    Rabbit anti-14-3-3 Sigma IHC Antibody, Affinity Purified

    预测反应

    Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Northern white-cheeked gibbon,Crab-eating macaque

    纯化方法

    Affinity Purified

    免疫原

    Between AA 198 and 248

    亚型

    IgG
  • 应用备注

    IHC-IF: 1:50 - 1:500

    IHC: 1:100 - 1:500

    限制

    仅限研究用
  • 浓度

    50 μg/mL

    缓冲液

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    有效期

    12 months
  • 抗原

    14-3-3 sigma/SFN (SFN) (Stratifin (SFN))

    别名

    14-3-3 Sigma

    背景

    Background: 14-3-3 sigma was identified as an epithelial cell marker. It is part of the 14-3-3 family of proteins in which seven isoforms have been identified: beta, zeta, gamma, eta, epsilon, tau, and sigma. 14-3-3 proteins function as adaptors that bind with a number of partners to mediate various signaling pathways. 14-3-3 sigma is also called stratifin or HME1 and appears to function as a tumor suppressor whose expression can be downregulated via methylation. Loss of 14-3-3 sigma expression results in a defective G2/M phase checkpoint and appears to contribute to both epithelial and non-epithelial tumorigenesis.

    基因ID

    2810

    NCBI登录号

    NP_006133

    UniProt

    P31947

    途径

    p53 Pathway, Myometrial Relaxation and Contraction
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