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Recombinant CD25 抗体 (AA 222-272)

This 兔 单克隆 anti-CD25 antibody (Clone BLR158J) specifically detects CD25 in FACS, IHC 和 ICC. The antibody is reactive with 人 samples.
产品编号 ABIN7448898
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant CD25 抗体 (AA 222-272) (ABIN7448898)

抗原

See all CD25 (IL2RA) 抗体
CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This CD25 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

克隆位点

BLR158J
  • 抗原表位

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    AA 222-272

    原理

    Rabbit anti-CD25/IL-2R alpha Recombinant Monoclonal Antibody [BLR158J]

    纯化方法

    Purified

    免疫原

    between AA 222 and 272 (C-term)

    亚型

    IgG
  • 应用备注

    IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    250 μg/mL

    缓冲液

    Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2 - 8 °C

    有效期

    12 months
  • 抗原

    CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

    别名

    CD25/IL-2R alpha

    背景

    The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. The IL2 receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. [taken from NCBI Entrez Gene (Gene ID: 3559)].

    基因ID

    3559

    UniProt

    P01589

    途径

    JAK/STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
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