BMI1 抗体 (AA 276-326)
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Quick Overview for BMI1 抗体 (AA 276-326) (ABIN7448885)
抗原
See all BMI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 276-326
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原理
- Rabbit anti-BMI1 IHC Antibody, Affinity Purified
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预测反应
- Rat,X. tropicalis,Chicken,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Cat,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,African elephant,Tasmanian devil,Gray short-tailed opossum,Small-eared galago,Naked mole rat,Zebra finch,Chinese hamster,Duckbill platypus,White-tufted-ear marmoset,Little brown bat,Northern white-cheeked gibbon,Thirteen-lined ground squirrel
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纯化方法
- Affinity Purified
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免疫原
- Between AA 276 and 326
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亚型
- IgG
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应用备注
- 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
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限制
- 仅限研究用
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浓度
- 250 μg/mL
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缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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有效期
- 12 months
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- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
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别名
- BMI1
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背景
- Background: BMI1 (B lymphoma Mo-MLV insertion region 1 homolog) is a core component of the polycomb group (PcG) multiprotein PRC1 complex which plays an important role in transcriptional repression of gene expression during development. BMI1 association with RING protein 1B is important to the E3 ligase activity of RING1B in the PRC1 complex. BMI1 is an oncogene whose overexpression is associated with many types of human tumors and is a stem-cell marker and regulator of stem cell self-renewal.
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基因ID
- 648
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NCBI登录号
- NP_005171
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UniProt
- P35226
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途径
- Cell Division Cycle, Autophagy
抗原
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